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Oxidation of cysteine residues in EGFR enhances its kinase activity, leading to hyperactivation of growth signaling (Paulsen et al, 2011)

While incompletely understood, ferroptotic activation is categorized into intrinsic and extrinsic pathways (152)

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Bolton WD, Hofstetter WL, Francis AM, Correa AM, Ajani JA, Bhutani MS, Erasmus J, Komaki R, Maru DM, Mehran RJ, Rice DC , Roth JA, Vaporciyan AA, Walsh GL, Swisher SG

S.KamelM.Abdo IsmailA

Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial
