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The NanoinMicro strategy, which encapsulates nanoparticles within microparticles, enables efficient microparticle deposition in the lungs while facilitating the targeted delivery of nanoparticles, thereby harnessing their unique advantages as drug nanocarriers (Figure 1)

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These results strongly suggest that the six inhibitors known to bind MDM2 can release the p53 TAD and that this HTS inhibitor screening assay had acceptable sensitivity to detect the changes of AlphaLISA signal caused by the actions of the inhibitors

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