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Activation of D 2 receptors has been shown to blunt cocaine sensitization (Beyer and Steketee, 2002), while D 2 antagonists or receptor knockout generally does not greatly alter acute locomotor activation, sensitization, or CPP (Spyraki et al., 1982

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Appreciation is extended to Supaphich Suksa, PharmD, for critical review of the manuscript, and to the Guest Editor(s) for the invitation to contribute to the special collection Women in Translational Neuroscience 2025

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