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62nd Annual Meeting of the Association for Computational Linguistics 1037010388 (Association for Computational Linguistics, 2024)
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However, during high-fat diet (HFD) feeding, obesity and insulin resistance, the accumulation of medium-chain and long-chain acylcarnitines due to incomplete -oxidation may negatively regulate the expression of nuclear-encoded mitochondrial genes, further reducing mitochondrial number and function and creating a vicious metabolic cycle [33]
Research has shown that insulin or a high carbohydrate diet could raise the levels of carnitine in muscle tissue during exercise after supplementation for several weeks (Wall et al
In prespecified subgroup analyses of the pooled evidence, effects appeared more favorable in trials enrolling older adults (60 years
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