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Description
NNMT metabolizes nicotinamide into 1-methylnicotinamide (MNA), diverting it away from the NAD+ salvage pathway
Table 2
NAD+ supplementation (NAD+, NMN, NR) increases the supply of NAD+ precursors from outside the cell
& Lee, D
It is important to consult with healthcare professionals about all supplements and medicines to avoid potential interactions and ensure safe usage
By blocking NNMT, 5-amino-1MQ restores optimal NAD+ and SAM levels, improving cellular function before any external changes become visible
