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Lung cancer (LC) is one of the major causes of mortality due to cancer throughout the world, primarily due to difficulties in early detection and the restricted efficacy of conventional therapies
Moreover, ACT-389949 displayed greater efficacy for -arrestin recruitment, while efficacy of Gi activation was similar for both agonists
The glutathione (GSH) reactivity assay can be used to assess structure-reactivity relationships of cysteine-targeting covalent inhibitors
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