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Big Pharma has lost trust due to overcharging for drugs and overmarking products leading to harm, like Vioxx 20 years ago

however, since mTOR is also described as a nutrient stress sensor, it is difficult to determine whether this effect is due to direct targeting or the result of metabolic rewiring [23, 89,90,91,92]

doi: 10.1016/S0753-3322(02)00193-2 153 ChiltonFHDuttaRReynoldsLMSergeantSMathiasRASeedsMC

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PubMed , Parasitology , vol