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Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

Larger, more complex peptides generally degrade faster than shorter sequences

References Vukojevic J, Sikiric P, Seiwerth S, et al

This D-retro-inverso configuration preserves the three-dimensional side-chain topology of the original FOXO4 sequence maintaining functional mimicry of the FOXO4 forkhead domains interaction surface with p53 while conferring exceptional proteolytic stability compared to the native L-amino acid sequence

There was no standardized pain score or imaging to measure improvement
