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In addition to being a major circulating carbohydrate fuel, lactate can induce histone lactylation via the histone acetyltransferase P300 23,24 or act as a ligand for the G-protein-coupled receptor GPR81 25,26
ROS are formed by three major mechanisms in vivo: by reaction of oxygen with decompartmentalized metal ions ( Fig
In addition, there is a significant difference of serum level retinol between pre- and post-flight samples but not during flight
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