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Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity

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This not only serves as additional energetic resource, but also generates a number of biologically active molecules such as diacylglycerol, cholesterol, ceramide, sphingosine, PIP2, IP3 which are involved in the activation of a variety of signaling pathways associated with cancer progression, metastases and therapy resistance e.g

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This energy easily suffices for arbitrarily large pores, even for vesicles that do not experience shear stress with membrane tension \(\sigma =0.\) This estimation shows that all vesicles in our experiments could fission, if the pore formation energy would be the single decisive parameter