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Neuronal C/EBPbeta/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression

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By inhibiting molecular pathways driving fibroblast activation and collagen dysregulation, anti-fibrotic therapies such as pirfenidone and nintedanib demonstrate clinical potential to attenuate radiation-triggered tissue stiffening while preserving alveolar-capillary gas exchange capacity [27, 28]

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equal to 50,000 cells/well plated 48 h before the assay)

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doi:10.1016/j.amjcard.2008.03.007

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