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The importance of being open to changing ones opinion in science and medicine as new evidence emerges [4:15]

There is no clinical consensus on timing
Enter etanercept (Enbrel), the first drug approved by the U.S

Which is kind is scary

Park S, Dong X, Fisher TL, et al
A permeability-increasing drug synergizes with bacterial efflux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains