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(58) performed single-nucleus RNA sequencing (snRNA-seq) on DCM, HCM, and non-failing heart samples, which led to the identification of transcriptional alterations and cellular sub-population changes in disease states, particularly fibroblast activation characteristics, which expanded the current understanding of pathomechanisms

In addition, there are relevant interactions between the humoral immune response and the complement system, as described in a comprehensive review (104)

Systemic chemotherapy (dacarbazine, temozolomide, or carboplatin/paclitaxel) plays a crucial role for some patients with metastatic disease