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Semaglutide remains a cornerstone compound for GLP-1-based investigations, but the emergence of Tirzepatide, Retatrutide, and Cagrilintide opens new avenues for exploring dual and multi-receptor strategies

doi: 10.1016/j.neurol.2016.03.006 132 LehikoinenJ.NurmiK.AinolaM.ClancyJ.NieminenJ

This is achieved, in part, by modulating the expression of pro-angiogenic factors such as Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor 2 (FGF-2)

Material and methods: The studies were conducted on laboratory animals, in this case male and female albino rats

The New England journal of medicine, 350(20), 20422049

All mice received 2 days of 10 mL/kg body weight sterile saline subcutaneous injections before beginning the treatment phase to allow for acclimation to the handling and stress associated with injections