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Examples include tryptases recruiting inflammatory cells into the lungs, neutrophil elastase inactivating tissue inhibitors of metalloproteinases, MMPs inactivating alpha-1 antitrypsin and macrophage inflammatory protein-1

-L-Glu (L-Glu-OH)-OH 2 was obtained in a 90% yield

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Finally, direct comparative trials are essential to determine whether timing meaningfully alters physiological, biochemical, or clinical outcomes

FIGURE 2 To enhance circulation time and reduce immunogenicity, the uricase-loaded MSN/SeMSN (MSN@Uri/SeMSN@Uri) were coated with red blood cell (RBC) membranes, as previously reported (Figure 1)

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