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However, during myogenesis, GW182 detaches and HDAC4 loses 5cap and poly(A) tail, suggesting that loss of GW182 alone or in combination with changes in HDAC4 facilitates the transport of Ago2: miR-1 into mitochondria ( Figure 8A )

Caro M, Iturria I, Martinez-Santos M, Pardo MA, Rainieri S, Tueros I, Navarro V (2016) Zebrafish dives into food research: effectiveness assessment of bioactive compounds

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Translational research further corroborates the link between a deficiency of LAC in clinical phenotypes of TRD and certain aspects of inflammation [51, 58]