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Description
M1 macrophages, induced by Toll-like receptor ligands (e.g., LPS) or Th1 cytokines such as TNF-, IFN-, and colony-stimulating factor 2 (CSF2), are characterized by surface expression of TLR2, TLR4, CD80, and CD86 (84)

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These overexpressing cells had decreased oxidative modification of mitochondrial DNA and enhanced resistance to oxidant-induced cell death (215, 256)
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Effect of cogarette smoke and its condensates on alveolar epithelial cell injury in vitro