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Although published studies and reviews discuss promising activity in preclinical models, available human data remain limited, and findings from animal or cell studies should not be directly translated into human outcomes

Evaluation of the AlphaFold predicted model protein structures was performed using pLDDT (predicted Local Distance Difference Test) (Jumper et al., 2021), ProSA (Sippl, 1993), ERRAT (Laskowski et al., 1993), and assessment tools (clashscore and MolProbity (Williams et al., 2018)) integrated within the SWISS-MODEL workspace (Waterhouse et al., 2018)

Havir EA, McHale NA

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E.SinclairJ.ButtA.ChungY.-L.WorthingtonJ

Regular monitoring and early detection of these conditions allow for prompt interventions to prevent further complications