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This is what makes FOXO4-DRI a senolytic rather than a general cytotoxic agent
Thus, inhibition of the NLRP3 inflammasome by itaconate represents an anti-inflammatory function of itaconate

Stress is caused by several foreign stimuli, such as the daily stressful events, school grades of adolescents, and financial problems of adults, which can result in irritability

doi: 10.1021/acsami.2c10669 85 AghaAWaheedWAlamoodiNMathewBAlnaimatFAbu-NadaEet al

Neutralising Free Radicals: Free radicals can cause oxidative stress, which damages cells and DNA

Curr HIV Res 12:8596