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A temperature excursion above 30C, even for a few hours, begins to denature the peptide backbone and weaken copper coordination bonds
PLoS Biol 3, e68 (2005)

doi: 10.3233/jad-2010-1239 148 NeumannPLenzDEStreitWJBechmannI

3.3.1 Background Anxiety disorders represent a group of persistent neuropsychiatric conditions affecting approximately 4.05% of the global population, with prevalence rising by over 55% since 1990 (Javaid et al., 2023)

Nanomedicine (Lond) 2015;11:10031018
