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HIF-1-mediated expression of Foxo1 serves an important role in the proliferation and apoptosis of osteoblasts derived from childrens iliac cancellous bone

PfGrx shares 39% sequence identity with human Grx1, including a CPYC motif and a semiconserved GGC motif, and is well characterized in vitro and in roGFP2 assays in yeast 14,26,30,35

Frontiers in Endocrinology, 14 , 1245512

A second pressing need lies in developing robust in vivo and in vitro models to accurately simulate the comorbid disease state

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Zabochnichka-wiatek and Malinska, 2010)