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It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+

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Hepatology 75 , 11941203 (2022)

UV radiation (UVR) exposure can activate the cutaneous immune system by releasing pro-inflammatory factors, ROS, and inducing apoptosis in keratinocytes, thereby causing sterile inflammation or cancer (Tang et al., 2021)

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Bromobenzene-induced liver necrosis