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Glutathione is an antioxidant that is present in small amounts in most people, but some free radicals cause damage to it, resulting in cellular decay and eventually aging

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However, excessive activation of M2a macrophages may promote fibrosis in LN, indicating that moderate M2a activation is likely to be of significant importance for LN (Anders and Ryu 2011)

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The systemic administration of deferasirox often causes off-target effects in the liver and kidneys, while intraocular injection, though improving local concentration, is invasive (159)

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