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Either direction would significantly impact the peptide landscape
Among the 25 studies included in the qualitative synthesis (16 in the meta-analysis), 15 focused specifically on serum cobalamin changes (reported by baseline and post-treatment means and standard deviations in pg/mL) and 10 reported homocysteine outcomes (means and standard deviations in mmol/L)

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doi: 10.2337/db08-0331

The second, a chronic diabetic foot ulcer managed under standard outpatient conditions, falls within the RCTs eligibility framework and demonstrates outcomes achievable in the controlled trial population

TB-500 acts through actin-binding and cell migration
