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Fukuchi, N

doi: 10.1111/and.12762 129 NuhuFGordonASturmeyRSeymourA-MBhandariS

Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1 papers.ssrn.com Abstract Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood

Pharmacological or gene inhibition of glutathione transporters, including multidrug resistant protein 1, can block cell GSH release, reduce intracellular ROS levels and production of oxidized phosphatidylcholine, thereby inhibiting cell ferroptosis

Biochem Biophys Res Commun 503:27842791

5-Amino-1MQ (15mg) is a small-molecule NNMT inhibitor designed to increase NAD+ availability, enhance energy expenditure, and reduce fat cell size
