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Fenkci et al., 2008

In comparison to normal rats, the administration of PD led to raised levels of malondialdehyde, tumor necrosis factor-alpha, and transforming growth factor-beta in the renal tissue, as well as elevated levels of serum creatinine and blood urea nitrogen

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The allopurinol challenge test is an alternative method for diagnosing OTC deficiency when it isnt clear from the lab studies
