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Description
Certain antioxidants can exhibit pro-oxidant activity under specific conditions

Reproduction 132: 217-232

The control group consisted of youthful patients, while senior patients ranged from 71 to 86 years of age

Results PM displayed various hallmarks of aggressive CRC biology

Oxidative biotransformation of S-Me-DDC forms S-diethylthiomethylcarbamate (S-Me-DTC), which could be further oxidized to S-Me-DTC-sulphoxide and S-Me-DTC-sulphone metabolites, respectively ( Pharmacodynamics of Disulfiram Ethanol metabolism in the liver predominantly relies on the action of ALDH isozymes and a minor amount of ethanol is metabolised through P450 mono-oxygenases and catalases

Front Pharmacol 13:924817
