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With the deepening of research, apoptosis, necroptosis, pyroptosis, autophagy and ferroptosis have been clearly recognized as RCD modalities that play central roles in tumorigenesis, immune evasion, and therapeutic response

Certain muscle groups observed in murine models, including the rectus abdominis, psoas major , and paraspinal muscles, showed a more pronounced increase in muscle density and volume, as well as a reduction in intramuscular fat content, than those observed in controls

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doi: 10.1016/j.yjmcc.2009.02.021
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Simultaneously, HGF is always acted as a potent inducer of lymphangiogenesis, angiogenesis, and tumor growth through promoting tumor cell invasion and metastasis (Cienfuegos et al., 2014