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These findings are complemented by the identification of several single-nucleotide polymorphisms (SNP) in GKRP, the protein that inhibits and sequesters GCK during fasting, that strongly associate with lower fasting glucose and insulin resistance coupled with increased blood and liver TAGs (243, 296)

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14,15 Extreme stress and eating disorders can disrupt hypothalamic signaling, leading to ovarian dysfunction and anovulation

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33 JeffreyL.NeulKaufmannW

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antioxidant potential, physiological function and role in disease

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Mice were fasted overnight (15 h) and injected i.p

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Pharmacopsychiatry 2006

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