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1,961 participants with BMI of 30+ (or 27+ with at least one weight-related condition) received either semaglutide 2.4 mg or placebo weekly for 68 weeks, alongside lifestyle intervention

MHC alleles are grouped into supertypes based on overlapping peptide binding properties, and A*11:01 belongs to the HLA-A3 supertype (hereafter, A3 supertype)

Expert Rev Gastroenterol Hepatol 13:10231031 Davies JS (2003) The cyclization of peptides and depsipeptides

Choline: A nutrient that supports liver function, helps metabolize fats, and assists in the transport of fats and cholesterol

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