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Despite the significance of SLC1A5 in some cancer cells, there are few specific and effective SLC1A5-inhibiting drugs 89

It is added because it addresses two specific and significant clinical problems that arise from GLP-1 receptor agonist therapy: nausea at treatment initiation and progressive B12 depletion over the course of long-term use

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Our overall goal is to understand Parkinsons disease better, efficiently program and adjust DBS systems based on each patients neurophysiological signals, and ultimately minimize the variability of outcomes and DBS costs, so this therapy is effective and accessible for more patients, says the projects principal investigator, David Escobar, PhD, Director of Cleveland Clinics Neural Dynamics and Modulation Laboratory