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These investigations should include evaluation of different administration routes, treatment frequencies, and treatment durations to optimize therapeutic protocols

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[Crossref] Chalupsky K, Kracun D, Kanchev I, Bertram K, Grlach A (2015) Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase