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An increase in FFA efflux from adipose tissue to liver can result in insulin resistance in the liver and GH is known to antagonise insulin action by this mean [183]

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If it impacts the testicular microenvironment, it could enhance sperm count or motility, but data are limited and the mechanism is different than how it might act in ovaries or endometrium

It also addresses the associated adverse effects, limitations, and controversies

Among its several functions, CGRP has been found to stimulate the proliferation and differentiation, and to reduce the apoptosis of osteoprogenitor cells [63, 64, 75, 79, 231]