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Download figure Open in new tab Download powerpoint Figure 3 Working model of MET in KRAS-mutant NSCLC

ABCG2 gene mutation has a significant effect on UA, especially the amino acid substitution in Q141K , which leads to risk of hyperuricaemia and gout (Wen et al., 2015

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The syndrome cannot cause severe indirect hyperbilirubinemia in neonates by itself, but it may have a summative effect on rising bilirubin when combined with other factors, [11] for example in the presence of increased red blood cell destruction due to diseases such as G6PD deficiency

However, despite these advances, traditional precision oncology approaches, which combine METTL3-14-WTAP activators and MAPK inhibitors, have not yet achieved satisfactory results in the treatment of thyroid cancer [28]