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In the A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome (APPROACH) trial (NCT02211209), which was a phase 3 trial including 66 patients with familial chylomicronemia syndrome, volanesorsen reduced APOC3 by 84% and TGs by up to 77% at 3 months [29]

World Acad Sci J [Internet]

Mol Metab (2019) 21:5167

Absorbance (590nm) was measured using a spectrophotometer (BioTek Epoch Microplate reader)

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