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[0524] In various embodiments the intracellular domain or otherwise the cytoplasmic domain comprises, one or more costimulatory signaling region(s), and in various embodiments, a zeta chain portion
Or in the very least, in addition to
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doi:10.1530/ERC-17-0153 Russell, Nicholas, and Mathis Grossmann
It has also been demonstrated to improve symptoms in colitis patients and DSS-induced colitis in mice [264]
