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Description
In the STEP-1 trial, 1,961 patients were followed for 68 weeks and underwent randomization to semaglutide or placebo plus lifestyle intervention resulting in14.9% weight loss in the semaglutide group versus 2.5% in the placebo group [33]
In clinical trials, specific agents have demonstrated significant benefits in glycemic control, with some (liraglutide, semaglutide, and dulaglutide) showing cardiovascular risk reduction in dedicated outcome trials
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