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1 Introduction Vitamins of the B complex comprise a group of eight water-soluble vitamins that play a crucial role in maintaining optimal neurological function, such as energy production, DNA/RNA synthesis/repair, genomic and non-genomic methylation, and synthesis of neurochemicals ( Figures 1 , 2 ) ( Figure 1 Figure 2 Thiamine (B1) deficiency is often associated with beriberi, a syndrome mainly characterized by polyneuritis and/or cardiovascular symptoms ( In conclusion, B vitamins are essential for both catabolic and anabolic metabolism functioning as coenzymes in numerous processes vital to cellular physiology, including brain and nervous system activities ( Table 1 )

TGF- induces miR-182 to sustain NF-B activation in glioma subsets

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Nagabhyru, J

doi: 10.1016/S0197-4580(03)00033-2 62 CarmenR.ChongC.-Y

This regulatory status means long-term human safety data remains limited compared to FDA-approved drugs