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Fungal Biol Biotechnol 10:16

The perfect linker ensures adequate stability of the cytotoxic drug in the circulation, effectively prevents premature release of the drug, effectively promotes the release of the cytotoxic drug in the targeted tumor cells, and strongly promotes the efficacy and tolerability of a successful ADC

doi:10.1007/s10549-007-9873-4

Similar protection was reported in anxiety models

The reaction mixture was quenched by water (20 mL) and extracted with dichloromethane (310 mL)
