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Nonetheless, there have recently been concerns about the combination's potential public health implications

Related articles Related Qustion Melanotan II: Promising Skin Tanning Peptide with Potential Renal Infarction Risk Feb 18, 2024 Melanotan II enhances skin pigmentation via MC1R activation but poses safety concerns, including renal infarction, necessitating cautious use and further investigation

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While it is important to note that skin pigmentation could be considered objectionable by certain populations, it is not normally considered one of the SAEs outlined by the FDA and ICH E2A/E6 guidelines (142, 143)