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, Induction of cardiac Angptl4 by dietary fatty acids is mediated by PPAR/ and protects against oxidative stress: P18

found that 27HC increases MMP9 expression and EMT through STAT-3 activation, thus promoting breast cancer migration and invasion [182]

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DEMOGRAPHIC ASPECT An extensive search of published case reports and review literatures on LHS since 1970 was performed based on the key words LaugierHunziker syndrome, Laugier-Hunziker-Baran syndrome, essential lenticular melanotic pigmentation, idiopathic lenticular mucocutaneous pigmentation, Laugier and Hunziker pigmentation, Laugiers disease, or longitudinal melanonychia. Most of the studies that were assessed and studied were in English

However, none of the patients enrolled in this study was overweight (BMI = 17.0 4.4 kg/m 2 ), and the lean body mass did not differ between the congenital hypothyroid patients and the healthy controls (data not shown), suggesting that the hepatocytes might be the primary site of TG deposition in these patients