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For example, in obesity, increased leptin levels bind to leptin receptors on astrocytes, activating the JAK/STAT signaling pathway

10.3945/an.112.003517 58 LivingstoneT

Reactive aldehydes also form adducts with DNA, selectively mutating bases and inducing strand breakage

doi:10.1186/s12967-017-1179-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 16.Kanazi GE, El-Khatib MF, Yazbeck-Karam VG, Hanna JE, Masri B, Aouad MT
