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Jrgensen ME, Bjerregaard P, Gyntelberg F, Borch-Johnsen K, Backer V, Becker U, Jrgensen T, Mulvad G

The mineral magnesium is essential to the function of over 300 biochemical enzyme processes in the body

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The lower chamber was added with various materials supplemented with 10% FBS, while serum-free DMEM was added to the upper chamber

To counter the enhanced efflux because of proteins like P-gp, overtly expressed in cancer cells, a higher dosage of the chemotherapeutic agent is considered, which would then directly lead to systemic toxicity

2023;21 doi: 10.1016/j.ebr.2022.100581