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An unanticipated observation was that black C57BL/6-HGF mice produced spontaneous melanomas without ultraviolet exposure, although spontaneous melanomas were not found in albino C57BL/6-c-HGF transgenic mice and were rare in albino FVB-HGF mice 9

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Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor

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Nature 467, 233236
