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The body processes and eliminates the peptide quickly rather than building up concentrations over time

doi:10.1097/ogx.0000000000000732 Lee CC, Su YC, Chien SH, et al
GH secretion is especially associated with slow wave sleep (SWS stages 3 and 4) (473)

The one-to-three-hour dihexa half life remains constant throughout multi-day or multi-week protocols, which is why daily dosing maintains consistent peak plasma concentrations without dose escalation

Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data
