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Specifically, it has been evidenced that berberine impairs the formation of the PPAR-NF-B transcriptional complex, downregulates CREB and EGR-1 expressions, and consequently suppresses cellular proliferation and inflammatory responses (91)

identified the first small-molecule potentiator of SLC39A8, efavirenz (EFV), through a drug repurposing screen

This also reflects that the activity of the MET channel may be regulated to some extent by changing the lipophilic ability of the compounds that affect the MET channel

2015 April 132 (1):63-84

61 , e202116282 (2022)
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