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Aquilano K, Baldelli S, Ciriolo MR (2014) Glutathione: new roles in redox signaling for an old antioxidant

10.1152/japplphysiol.00397.2007 44

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The study looked at whether a combination of cardiovascular outcomes (heart attack, stroke, cardiac death, mini-stroke, urgent heart surgery for coronary disease) were more common in the allopurinol or the febuxostat group

Activated IGF-1/IGF-1R signaling likely stimulates PCa cell dissemination to other organs by modifying cell adhesion and mobility, facilitating angiogenesis, and increasing the osteoblastic activity of neoplastic cells (Figure 1) [58]
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