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Research has also shown that under serine-deficient conditions, pancreatic ductal adenocarcinoma (PDAC) cells maintain intracellular serine levels by upregulating PHGDH, adapting to the harsh microenvironment and promoting tumor progression (74)
10.1155/2015/607271 295 XuJ.WangA.MengX.YalkunG.XuA.GaoZ.et al (2021)
In addition to supplying building blocks for GSH synthesis, GSH derived from astrocytes helps to support astrocyte regulation of the immune system
Tavender TJ, Bulleid NJ
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