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Glutathione is a natural detoxifier with anti-ageing properties, protecting the skin barrier against oxidative damage (which can lead to wrinkles)

Its cysteinyl thiol group neutralizes reactive oxygen species, donates electrons in glutathione peroxidase reactions, and forms conjugates with electrophilic xenobiotics via glutathione S-transferases

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Knockdown of GPx1 in macrophages from healthy volunteers resulted in increased H2O2-induced cell death reminiscent of that observed with macrophages from CD

vulgaris extracts at a concentration of 0.5%