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Mouth Ulcers and Angular Cheilitis These may not seem like skin issues, but theyre often the first clue to internal deficiencies

The therapy involves using a sealed wound dressing attached to a pump to create a negative pressure environment in the wound

At the cellular level, B12 acts as a cofactor for two critical enzymatic reactions: Methionine synthase converts homocysteine to methionine, essential for DNA methylation and synthesis Methylmalonyl-CoA mutase involved in fatty acid metabolism and myelin production By restoring adequate B12 levels, injections enable normal red blood cell maturation in the bone marrow, correcting the megaloblastic anaemia

By the way, even if you dont have pernicious anemia, but a severe B12 deficiency due to other causes, B12 shots are still the way to go

3- AMP- (AMPK)

Correcting a genuine deficiency can meaningfully change how you feel within weeks